Tuesday, April 23, 2013

PLN 5

                         Medicinal Chemsitry

  Medicinal chemistry is discipline at the branch of chemistry, especially synthetic organic chemistry, and pharmacology and various other biological specialties, where they are involved with design, chemical and development for market of pharmaceutical agents, or bio-active molecules (drugs). They are some specific drugs called antipsychotic drugs andantidepressants which are used to deal with the patients who have this kind of disorders.
     For the medicines I mentioned above are made as compounds. Usually the elements are carbon, hydrogen and oxygen. Maybe all of the drug compound are composed as same elements, but the different structure they have may cause them have different functions and usage. Besides, this kind of compound are commonly called organic compounds. They often divided into the broad classes of small organic molecules (atorvastatin, fluticasone, clopidogrel) and "biologics". The latter of which are most often medicinal preparations of proteins (natural and recombinant antibodies, hormones). 
  Inorganic and organ metallic compounds are also useful as drugs Since of this, learning basic knowledge and analyze the structure of them become significant. In particular, medicinal chemistry in its most common guise—focusing on small organic molecules—encompasses synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology. In a word, it involves chemical aspects of identification, and then systematic, thorough synthetic alteration of new chemical entities to make them suitable for therapeutic use. 
  So,make a specific Medicine using chemistry become a hard and specific work, unless people are familiar with chemistry, they can not figure out anything about it. The study includes synthetic and computational aspects of the study of existing drugs and agents in development in relation to their bioactivities, understanding their structure-activity relationships (SAR). 

Monday, April 15, 2013

PLN4

                                           The use of chemistry in the future.
   People began to pay attention to chemistry in 17 and had a development in 18 century under Boyle and Lavoisier's leading. Thanks to them, chemistry got the highest that time.
   Nowadays, chemistry is a major and is relevant about lots of other subjects such as psysics psychology and biology. It provides something that psysics can not explain and gives the solutions by using chemical reactions and the molecular structrue.  What does that mean?
   The idea that chemistry has its advance and importance is obvious. In next three year, I may focus on chemistry as my major. I wonder if we can use chemistry to find humand and creation's secrets. For me, my aim is using my hands and brain to let chemistry to get a higher altitude which means chemistry may have more and more use in more aspects. Madame Curie and his husband died since of the element they named, which has a strong radiation. Using chemistry to creat a new kind of medicine to heal some chronic diseases.
  Most of the anticancer drugs are hydrophobic molecules with serious toxicity to normal tissues and cells. Although it is known for all of the patients who have to take the medine to keep their livies. As I know, everytime people take the toxic drugs, they suffer a lot for mental and soma.
They want to get rid of the horrible medicine but they need them to help them live. However, as long as they take too much of this kind of medicine, even their cancer is cured, they are still going to die since of the toxin from the drug they take every single day. However, without chemical drugs, are ther any other ways to deal with high death rate cancer? The answer is no.
  It I can, human can, finding out the method to make the non-toxic anticancer medicine, It must be the best and most significent inventmen in 21 century. Learning the strucures and analysing the composition of each compound is the first step. Then there are many other secrets of chemistry is waiting us to find out.
  Can we?