Tuesday, April 23, 2013

PLN 5

                         Medicinal Chemsitry

  Medicinal chemistry is discipline at the branch of chemistry, especially synthetic organic chemistry, and pharmacology and various other biological specialties, where they are involved with design, chemical and development for market of pharmaceutical agents, or bio-active molecules (drugs). They are some specific drugs called antipsychotic drugs andantidepressants which are used to deal with the patients who have this kind of disorders.
     For the medicines I mentioned above are made as compounds. Usually the elements are carbon, hydrogen and oxygen. Maybe all of the drug compound are composed as same elements, but the different structure they have may cause them have different functions and usage. Besides, this kind of compound are commonly called organic compounds. They often divided into the broad classes of small organic molecules (atorvastatin, fluticasone, clopidogrel) and "biologics". The latter of which are most often medicinal preparations of proteins (natural and recombinant antibodies, hormones). 
  Inorganic and organ metallic compounds are also useful as drugs Since of this, learning basic knowledge and analyze the structure of them become significant. In particular, medicinal chemistry in its most common guise—focusing on small organic molecules—encompasses synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology. In a word, it involves chemical aspects of identification, and then systematic, thorough synthetic alteration of new chemical entities to make them suitable for therapeutic use. 
  So,make a specific Medicine using chemistry become a hard and specific work, unless people are familiar with chemistry, they can not figure out anything about it. The study includes synthetic and computational aspects of the study of existing drugs and agents in development in relation to their bioactivities, understanding their structure-activity relationships (SAR). 

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